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| Joanne Whalley | ...Jacqueline Bouvier Kennedy - Jackie O stepped into the White House and became America's First Lady to husband John F Kennedy, JFK. | Jackie Bouvier Kennedy Onassis |
| Tim Matheson | ... | John F. Kennedy |
| Tom Skerritt | ... | Joseph P. 'Joe' Kennedy |
| Frances Fisher | ...
| Janet Lee Bouvier Auchincloss |
| Andrew McCarthy | ...Biography focusing on the former First Lady's years in DC, from working as a newspaper's "Inquiring Camera Girl" to meeting and being courted by Rep. Jack. | Robert 'Bobby' Kennedy |
| Philip Baker Hall | ... | Aristotle Onassis |
| Diane Baker | ... | Rose Kennedy |
| Jerry Adler | ...
| Maurice Tempelsman |
| Chuck Shamata | ...The kennedys This biographical miniseries, based on the best seller by C. David Heymann, starts when Jackie Kennedy was working after college.A woman named jackieBiography focusing on the former First Lady's years in DC, from working as a newspaper's "Inquiring Camera Girl" to meeting and being courted by Rep. Jack.Jacqueline Bouvier Kennedy - Jackie O stepped into the White House and became America's First Lady to husband John F Kennedy, JFK. | Pierre Salinger |
| Fred Ward | ... | John Vernon 'Black Jack' Bouvier III |
| Bronwen Booth | ... | Lee Bouvier |
| Jennifer Van Dyck | ...
| Caroline Kennedy (as Jennifer Van Dyke) |
| Jeffrey Pierce | ... | John F. Kennedy Jr. |
| Jacob Richmond | ... | Edward 'Ted' Kennedy |
| David Francis | ...
| Hugh D'Auchincloss (as Davis Francis) |
| Gillian Ferrabee | ...As she grapples with unimaginable grief and trauma following President John F. Kennedy's assassination, “Jackie's” faith and strength lead her to a new life. | Ethel Kennedy |
| Johanna Nutter | ... | Eunice Kennedy |
| Sara Bradeen | ... | Jean Kennedy |
| Anne-Catherine LeBeau | ...
| Pat Kennedy
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